Detail of the student project

Topic:Předzpracování obrazových dat funkční magnetické rezonance
Department:Katedra kybernetiky
Supervisor:Ing. Milan Němý
Announce as:Diplomová práce, Bakalářská práce, Semestrální projekt
Description:Functional Magnetic Resonance Imaging (fMRI) studies have become increasingly popular both with clinicians and researchers as they are capable of providing unique insights into brain functions. Functional brain mapping is most commonly performed using the venous blood oxygenation level-dependent (BOLD) contrast technique. The magnitude of the BOLD signal is an indirect measure of neuronal activity, and is a composite which reflects changes in regional cerebral blood flow, volume, and oxygenation. In this project, the student will study the basic mechanisms of image forming with fMRI, most particularly resting-state fMRI (rs-fMRI). The student will design a pre-processing pipeline for rs-fMRI data, apply the pipeline to a cohort of Alzheimer’s disease patients, and statistically compare the resulting activation pattern with healthy controls. Contact email:
Bibliography:1. Soares, José M., et al. "A Hitchhiker's guide to functional magnetic resonance imaging." Frontiers in neuroscience 10 (2016): 515.
2. Lv, Han, et al. "Resting-state functional MRI: everything that nonexperts have always wanted to know." American Journal of Neuroradiology 39.8 (2018): 1390-1399.
3. Lee, Megan H., Christopher D. Smyser, and Joshua S. Shimony. "Resting-state fMRI: a review of methods and clinical applications." American Journal of neuroradiology 34.10 (2013): 1866-1872.
Responsible person: Petr Pošík