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Diploma thesis:HLA Consanguinity of Czechs and Other Nations ( PDF )
Author:Kábrt Lukáš
Supervisor:doc. Ing. Lenka Lhotská CSc.
Keywords:
Abstract:The goal of this thesis is search for a technique, which can calculate genetic distance between two populations based on the knowledge of their HLA, its implementation and using this technique for calculation genetic distance between Czechs and other nations. The results will be published on the HLA Explorer web page. This thesis can be divided into three the most important parts - theoretical part, implementation part and experimental part. The basics of population genetics and properties of HLA along with various methods for genetic distance calculation are described in theoretical part. In the Implementation chapter are explained used technologies and algorithms. Experimental part contains results and their analysis from the historical and geopolitical point of view. Important part of this thesis is electronic attachment with implementation and source code for selected genetic distance calculation method.
Submited:Jun 2009
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