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Diploma thesis:MR Signal Analysis ( PDF )
Author:Saudek Erik
Supervisor:doc. Ing. Daniel Novák Ph.D.
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Abstract:Magnetic resonance has proven to be a successful method of in-vivo imaging. Although MRI can help detect various pathologies, its ability to classify the nature of the pathological tissue is limited. Magnetic resonance spectroscopy allows identifying metabolite content of the tissue and estimating the metabolite concentration. Map of metabolite concentration along with the MR image allows proper classification of many pathologies, for example progressive tumorous tissue identification in human brain. Standard methods used to analyze nuclear magnetic resonance spectra such as singular value decomposition or curve fitting algorithms are very time consuming taking several minutes to analyze spectrum from a single voxel. To analyze the spectra from a chemical shift imagine sequence (CSI) in maximal resolution hundreds of spectra need to be processed. The suggested ANN framework proved to be much faster. Networks were trained on the outputs of LCModel curve fitting algorithm. Time needed to process a spectrum from a single voxel was reduced to the order of seconds. The total time needed to analyze a CSI in full resolution (hundreds of spectra) was significantly reduced to 5 minutes.
Submited:May 2008
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